This study investigates several students’ interpretations and meanings for negations of various mathematical statements with quantifiers, and how their meanings for quantified variables impact their interpretations and denials of these quantified statements. Eight students participated in three separate exploratory teaching interviews and were selected from Transition-to-Proof and advanced mathematics courses beyond Transition-to-Proof. In the first interview, students were asked to interpret mathematical statements from Calculus contexts and provide justifications and refutations for why these statements are true or false in particular situations. In the second interview, students were asked to negate the same set of mathematical statements. Both sets of interviews were analyzed to determine students’ meanings for the quantified variables in the statements, and then these meanings were used to determine how students’ quantifications influenced their interpretations, denials, and evaluations for the quantified statements. In the final interview, students were also be asked to interpret and negation statements from different mathematical contexts. All three interviews were used to determine what meanings comprised students’ interpretations and denials for the given statements. Additionally, students’ interpretations and negations across different statements in the interviews were analyzed and then compared within students and across students to determine if there were differences in student denials across different moments.