Testing the Human Small Intestine under Different Preservation Conditions Segmentally with a Look Into the Ethics of Health Insurance Involvement

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Description
Intestinal Transplant is becoming more prevalent with time as an powerful alternative to other therapies for intestinal failure such as parenteral nutrition. The small intestine is an organ especially susceptible to ischemia, or the lack of blood and oxygen supply

Intestinal Transplant is becoming more prevalent with time as an powerful alternative to other therapies for intestinal failure such as parenteral nutrition. The small intestine is an organ especially susceptible to ischemia, or the lack of blood and oxygen supply to an organ. I studied ischemia at Yale Medical School in the lab of Dr. John Geibel. The purpose of this study was to find which kind of solution best protects the intestine from ischemia as well as which segments of the intestine are more susceptible to ischemic damage. This was done by cold static storage as well as through perfusing the organ with a unit developed in the lab called the Intestinal Perfusion Unit (IPU). Intestines were procured from deceased donors following the protocol for handling human specimen and then flushed with either the University of Wisconsin (UW) solution or the Histidine-tryptophan-ketoglutarate solution (HTK). It was found that the jejunum is more susceptible ischemia than the ileum. It was also found that in the jejunum, when using UW solution there was less damage then when using HTK. Clinically, this means that in transplant, if the ileum part is used, there is less risk for ischemic damage. The potential applications of this research raise many ethical issues related to organ transplantation more broadly. The ethical issues include but are not limited to: consent, distribution and need-based donation, transplant tourism, and cost and access. The costs for transplant are exorbitant for the average American. Private insurance companies and Medicare have no policy for intestinal transplant and are therefore not covering many patients in need. In this thesis, I briefly explore the role of insurance companies in the equitable distribution of innovative medical interventions.
Date Created
2018-05
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No Worker Left Behind: An Analysis on a Universal Basic Income

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Description
Many fear that the growth of automation and artificial intelligence will lead to massive unemployment since human labor would no longer be needed. Although automation does displace workers from their current jobs, it is unclear the total net effect on

Many fear that the growth of automation and artificial intelligence will lead to massive unemployment since human labor would no longer be needed. Although automation does displace workers from their current jobs, it is unclear the total net effect on jobs this period of advancement will have. One possible solution to help displaced workers is a Universal Basic Income. A Universal Basic Income(UBI) is a set payment paid to all members of society regardless of working status. Compared to current unemployment programs, a Universal Basic Income does not restrict participants in how to spend the money and is more inclusive. This paper examines the effects of a UBI on a person's motivation to work through a study on current college students. There is reason to believe that a Universal Basic Income will lead to fewer people working as people may become dependent on a base payment to meet their basic needs and not look for work. In addition, some people may drop out of their current jobs and rely on a UBI as their main form of income. The current literature does not offer a consensus opinion on this relationship and more studies are being completed with the threat of mass unemployment looming. This study shows the effects of a UBI on participants' willingness to work and then applies these results to the current economic model. With these results and new economic model, a decision about future policies surrounding a UBI can be made.
Date Created
2018-05
Agent