Producing a brighter electron beams requires the smallest possible emittance from the cathode with the highest possible current. Several materials like ordered surface, single-crystalline metal surfaces, ordered surface, epitaxially grown high quantum efficiency alkali-antimonides, topologically non-trivial Dirac semimetals, and nano-structured confined emission photocathodes show promise of achieving ultra-low emittance with large currents. This work investigates the various limitations to obtain the smallest possible emittance from photocathodes, and demonstrates the performance of a novel electron gun that can utilize these photocathodes under optimal photoemission conditions. Chapter 2 discusses the combined effect of physical roughness and work function variation which contributes to the emittance. This is particularly seen in polycrystalline materials and is an explanation for their higher than expected emittance performance when operated at the photoemission threshold. A computation method is described for estimating the simultaneous contribution of both types of roughness on the mean transverse energy. This work motivates the need for implementing ordered surface, single-crystalline or epitaxially grown photocathodes. Chapter 3 investigates the effects of coulomb interactions on electron beams from theoretically low emittance, low total energy spread nanoscale photoemission sources specifically for electron microscopy applications. This computation work emphasizes the key role that image charge effects have on such cold, dense electron beams. Contrary to initial expectations, the primary limiter to beam brightness for theoretically ultra-low emittance photocathodes is the saturation current. Chapters 4 and 5 describe the development and commissioning of a high accelerating gradient, cryogenically cooled electron gun and photoemission diagnostics beamline within the Arizona State University Photoemission and Bright Beams research lab. This accelerator is unique in it's capability to utilize photocathodes mounted on holders typically used in commercial surface chemistry tools, has the necessary features and tools for operating in the optimal regime for many advanced photocathodes. A Pinhole Scan technique has been implemented on the beamline, and has shown a full 4-dimensional phase space measurement demonstrating the ability to measure beam brightness in this gun. This gun will allow for the demonstration of ultra-high brightness from next-generation ultra-low emittance photocathodes.

Millimeter astronomy unlocks a window to the earliest produced light in the universe, called the Cosmic Microwave Background (CMB). Through analysis of the CMB, overarching features about the universe's evolution and structure can be better understood. Modern millimeter-wave instruments are constantly seeking improvements to sensitivity in the effort to further constrain small CMB anisotropies in both temperature and polarization. As a result, detailed investigations into lesser-known processes of the universe are now becoming possible. Here I present work on the millimeter-wavelength analysis of z ≈ 1 quiescent galaxy samples, whose conspicuous quenching of star formation is likely the result of active galactic nuclei (AGN) accretion onto supermassive black holes. Such AGN feedback would heat up a galaxy's surrounding circumgalactic medium (CGM). Obscured by signal from cold dust, I isolate the thermal Sunyaev-Zel'dovich effect, a CMB temperature anisotropy produced by hot ionized gas, to measure the CGM's average thermal energy and differentiate between AGN accretion models. I find a median thermal energy that best corresponds with moderate to high levels of AGN feedback. In addition, the radial profile of cold dust associated with the galaxy samples appears to be consistent with large-scale clustering of the universe. In the endeavor of increasingly efficient millimeter-wave detectors, I also describe the design process for novel multichroic dual-polarization antennas. Paired with extended hemispherical lenslets, simulations of these superconducting antennas show the potential to match or exceed performance compared to similar designs already in use. A prototype detector array, with dual-bowtie and hybrid trapezoidal antennas coupled to microwave kinetic inductance detectors (MKIDs) has been made and is under preparation to be tested in the near future. Finally, I also present my contributions to the cryogenic readout design of the Ali CMB Polarization Telescope (AliCPT), a large-scale CMB telescope geared towards searching the Northern Hemisphere sky for a unique `B-mode' polarization expected to be produced by primordial gravitational waves. Cryogenic readout is responsible for successful interfacing between room temperature electronics and sensitive detectors operating on AliCPT's sub-Kelvin temperature focal plane. The development of millimeter-wave instruments and future endeavors show great potential for the overall scientific community.

The spectra of predicted particles from elementary quark models (CQMs) are expansive, accurate for the low-lying spectra, but incomplete. The GlueX experiment at Jefferson Lab is a vehicle to study medium energy photoproduction of hadronic states. The primary goal of the GlueX collaboration is to study Quantum Chromodynamics (QCD, also known as the strong nuclear force) and the nature of quark confinement. The GlueX collaboration uses a polarized photon beam incident on a liquid hydrogen target (LH2) to investigate the aftermath of photon-proton interactions.The cascade baryons, denoted by Ξ, are defined by having two, second-generation, strange quarks with an additional first-generation light quark (u or d). Experimentally, few cascades have been discovered, which is the antithesis of what most models expect. The cascades have some favorable attributes but are difficult to detect because the production cross sections are small and direct production is unlikely. Fortunately, in the 12 GeV era of the GlueX experiment, there is sufficient energy, beam time and data analysis tools for the detection of excited cascade states and their properties. From the reaction γp→K^+ K^+ Ξ^- π^0, the invariant mass spectra of Ξ^- π^0 system was surveyed for new possible resonances. The invariant mass spectrum has a strong Ξ(1530) signal with other smaller resonances throughout the spectrum. Preliminary cross sections for the Ξ(1530) that was photoproduced from the proton are presented at energies never before explored. While the Ξ(1530) couples almost exclusively to the Ξπ channel, there is an easily identifiable Ξ(1690) signal decaying Ξπ. Through the use of a simultaneous fitting routing of the Ξ*- mass spectra, I was able to observe the Ξ(1690) decaying to the KΛ, as well as to the Ξ-π0 branch. With additional statistics, a measurement of the branching ratio should be possible. Lastly, a partial wave analysis (PWA) was completed to verify that the total angular momentum of Ξ(1530) is J = 3/2 and consistent with having positive parity. Additionally, there is evidence of a potentially interesting feature slightly above the mass of the Ξ(1530) that should be more fully explored as new GlueX data becomes available.

Cubic boron nitride (c-BN), hexagonal boron nitride (h-BN), and semiconducting diamond all have physical properties that make them ideal materials for applications in high power and high frequency electronics, as well as radiation detectors. However, there is limited research on the unique properties and growth of c-BN or h-BN thin films. This dissertation addresses the deposition of c-BN via plasma enhanced chemical vapor deposition (PECVD) on boron doped diamond substrates. In-Situ X-ray photoelectron spectroscopy (XPS) is used to characterize the thickness and hexagonal to cubic ratio of boron nitride thin films. The effects of hydrogen concentration during the deposition of boron nitride are investigated. The boron nitride deposition rate is found to be dependent on the hydrogen gas flow. The sp2 to sp3 bonding is also found to be dependent on the hydrogen gas flow. Preferential growth of h-BN is observed when an excess of hydrogen is supplied to the reaction, while h-BN growth is suppressed when hydrogen flow is reduced to be the limiting reactant. Reduced hydrogen flow is also observed to promote preferential growth of c-BN. The hydrogen limited reaction is used to deposit c-BN on single crystal (100) boron-doped diamond substrates. In-situ ultra-violet photoelectron spectroscopy (UPS) and XPS are used to deduce the valence band offset of the diamond/c-BN interface. A valence band offset of -0.3 eV is measured with the diamond VBM above the VBM of c-BN. This value is then discussed in context of previous experimental results and theoretical calculations. Finally, UPS and XPS are used to characterize the surface states of phosphorus-doped diamond. Variations within the processing parameters for surface preparation and the effects on the electronic surface states are presented and discussed.

The GlueX experiment housed in Hall D of the Thomas Jefferson National Laboratory was created to map the light meson spectrum in order to contribute to the Standard Model of particle physics by strengthening our understanding of the strong interaction. GlueX is a medium-energy photoproduction experiment that utilizes a linearly polarized photon beam to create hadronic forms of matter. By mapping the light meson spectrum, the GlueX collaboration hopes to identify meson states forbidden by the Constituent Quark Model. As a main research objective, the GlueX collaboration is searching for hybrid $q\bar{q}g$ meson states that exhibit exotic quantum numbers. One hybrid meson candidate is the $\eta'_1$, which is predicted to decay to $K^\ast\bar{K}$ and have a mass near $2.3~\mathrm{GeV}$ (\citeauthor{qn_exotic_status}, \citeyear{qn_exotic_status}; \citeauthor{hybrid_mesons}, \citeyear{hybrid_mesons}). At this time, very few meson states have been identified in the $2.0~\mathrm{GeV}$ mass region. This dearth of evidence for existing states requires any tool developed to search for meson states above $2.0~\mathrm{GeV}$ must be verified by looking at known meson states. In order to search for the $\eta'_1$ hybrid meson candidate in $\gamma p \rightarrow pK^+K^-\gamma\gamma$ events, meson states decaying $K^\ast\bar{K}$ that contribute to the low mass region must be identified, defined in this document as particles having masses between $1400$ and $1600~\mathrm{MeV}$. Identifying what meson states exist in the low mass region is also critical to mapping the light meson spectrum and determining the quark-gluonic content of those meson states. The results of a partial wave analysis (PWA) of $\gamma p \rightarrow pX$ where $X\rightarrow K^\ast\bar{K}$ from $\gamma p \rightarrow pK^+K^-\gamma\gamma$ events in GlueX are presented. In the $J=0$ invariant mass distribution, the $\eta(1405)$ and $\eta(1475)$ are identified, adding to the debate as to whether two pseudoscalar mesons exist in the low mass region. For the $J=1$ distribution, the $f_1(1420)$ and $f_1(1510)$ axial vector mesons are seen, where the former helps further elaborate on the $E\iota$ puzzle of the twentieth century \citep{E_iota_puzzle}. With respect to the controversy of meson states in the low mass region, evidence for the existence of the $f_2(1430)$ meson is strengthened in the $J=2$ distribution, and the $f'_2(1525)$ state is seen. This work lays a foundation for the ASU Meson Physics Group to continue a wider search for hybrid mesons in the $\gamma p \rightarrow pK^+K^-\gamma\gamma$ reaction topology.

Precision measurements of kinematic correlation parameters of free neutron decayserve as a powerful probe of the Standard Model of particle physics. A wide array of Beyond the Standard Model physics theories can be probed by precision neutron physics. The Nab experiment will measure a, the electron-neutrino correlation coefficient, and b, the Fierz interference term. a is amongst the most sensitive decay parameters to λ = gA/gV , the ratio of the axial-vector and vector coupling constants in the weak force. Two important systematic considerations for the Nab experiment are average detector timing bias, which must be held to ≤ 0.3 ns, and energy calibration and linearity, which must be held to 1 part in 104 . Both systematics require an in depth understanding of charge collection in Nab’s Si detectors. Simulation of Si charge collection using numerical methods and the Shockley-Ramo Theorem has been completed. A variety of detector tests, including detector and amplification electronics acceptance testing have also been completed. Also included in this dissertation is my work with the Nab ultra-high vacuum and cryogenic system.

Treatment log files for spot scanning proton therapy provide a record of delivery accuracy, but they also contain diagnostic information for machine performance. A collection of patient log files can identify machine performance trends over time. This facilitates the identification of machine issues before they cause downtime or degrade treatment quality. At Mayo Clinic Arizona, all patient treatment logs are stored in a database. These log files contain information including the gantry, beam position, monitor units (MUs), and gantry angle. This data was analyzed to identify trends, which were then correlated with quality assurance measurements and maintenance records.

This research evaluates the capabilities of typical radiological measures and dual-energy systems to differentiate common kidney stones materials: uric acid, oxalates, phosphates, struvite, and cystine. Two different X-ray spectra (80 kV and 120 kV) were applied and the dual-energy ratio of individual kidney stones was used to figure out the discriminability of different materials. A CT cross-section with a prospective kidney stone was analyzed to see the capabilities of such a technique. Typical radiological measures suggested that phosphates and oxalate stones can be distinguished from uric acid stones while dual-energy seemed to prove similar effectiveness.

Seeking an upper limit of the Neutron Electric Dipole Moment (nEDM) is a test of charge-parity (CP) violation beyond the Standard Model. The present experimentally tested nEDM upper limit is 3x10^(26) e cm. An experiment to be performed at the Oak Ridge National Lab Spallation Neutron Source (SNS) facility seeks to reach the 3x10^(28) e cm limit. The experiment is designed to probe for a dependence of the neutron's Larmor precession frequency on an applied electric eld. The experiment will use polarized helium-3

(3He) as a comagnetometer, polarization analyzer, and detector.

Systematic influences on the nEDM measurement investigated in this thesis include (a) room temperature measurements on polarized 3He in a measurement cell made from the same materials as the nEDM experiment, (b) research and development of the Superconducting QUantum Interference Devices (SQUID) which will be used in the nEDM experiment, (c) design contributions for an experiment with nearly all the same conditions as will be present in the nEDM experiment, and (d) scintillation studies in superfluid helium II generated from alpha particles which are fundamentally similar to the nEDM scintillation process. The result of this work are steps toward achievement of a new upper limit for the nEDM experiment at the SNS facility.

The challenge of radiation therapy is to maximize the dose to the tumor while simultaneously minimizing the dose elsewhere. Proton therapy is well suited to this challenge due to the way protons slow down in matter. As the proton slows down, the rate of energy loss per unit path length continuously increases leading to a sharp dose near the end of range. Unlike conventional radiation therapy, protons stop inside the patient, sparing tissue beyond the tumor. Proton therapy should be superior to existing modalities, however, because protons stop inside the patient, there is uncertainty in the range. “Range uncertainty” causes doctors to take a conservative approach in treatment planning, counteracting the advantages offered by proton therapy. Range uncertainty prevents proton therapy from reaching its full potential.

A new method of delivering protons, pencil-beam scanning (PBS), has become the new standard for treatment over the past few years. PBS utilizes magnets to raster scan a thin proton beam across the tumor at discrete locations and using many discrete pulses of typically 10 ms duration each. The depth is controlled by changing the beam energy. The discretization in time of the proton delivery allows for new methods of dose verification, however few devices have been developed which can meet the bandwidth demands of PBS.

In this work, two devices have been developed to perform dose verification and monitoring with an emphasis placed on fast response times. Measurements were performed at the Mayo Clinic. One detector addresses range uncertainty by measuring prompt gamma-rays emitted during treatment. The range detector presented in this work is able to measure the proton range in-vivo to within 1.1 mm at depths up to 11 cm in less than 500 ms and up to 7.5 cm in less than 200 ms. A beam fluence detector presented in this work is able to measure the position and shape of each beam spot. It is hoped that this work may lead to a further maturation of detection techniques in proton therapy, helping the treatment to reach its full potential to improve the outcomes in patients.