The purpose of this study was to determine the relationship between extracurricular activities and self-regulation in 400 five year old twin children. Extracurricular activities were assessed using the Health and Behavior Questionnaire, and self-regulation was assessed using the Children's Behavior Questionnaire. While there initially was a significant correlation between extracurricular activities and self-regulation, that correlation became non-significant when controlling for SES and sex in a mixed model regression model. Nearly all of the children who did not participate in extracurricular activities came from lower SES families, leading to a lack of a "control group" for the high SES families. When only taking into account the lower SES half of the sample, the correlation between extracurricular activities and self-regulation became stronger and the correlation between SES and self-regulation became non-significant. Extracurricular activities do appear to promote self-regulation in children coming from low SES families, yet their effects on children coming from high SES families is still unknown.

Drospirenone (DRSP) is a novel, pharmacologically unique synthetic progestin with properties more similar to the endogenous progestogen, progesterone, than any other progestin currently on the market. While a significant amount of research has been conducted on the risks associated with DRSP, the impact of DRSP on cognition, especially in reference to learning and memory, is not well understood. However, it is imperative to fully understand the cognitive effects of DRSP, both alone and in combination with EE (as taken in a combined oral contraceptive [COC]), so that women and their physicians can make a fully-informed decision when deciding to take a DRSP-containing COC. Study 1 examined the effects of three doses of DRSP in order to determine the optimal dose for combining with EE, and found that the medium dose of DRSP (30 µg/day) enhanced spatial working memory performance. In Study 2, the medium dose of DRSP from Study 1 was combined with low (0.125 µg/day) and high (0.3 µg/day) doses of EE to examine the effects of DRSP as taken with EE in a COC. The results from Study 2 indicated that when DRSP was combined with a low, but not high, dose of EE, spatial working memory impairments were seen at the highest working memory load. Anxiety-like behavior was evaluated using the OFT, and DRSP was shown to decrease measures of anxiety-like behavior. Additionally, while treatment with a high dose of EE decreased several measures of anxiety-like behavior, a low dose of EE did not, suggestive of a dose response. Taken together, the findings presented from both studies suggest that some of the cognitive effects of the combination of DRSP with EE are different than those of either hormone administered on its own. Further exploration in a preclinical, ovary-intact animal model is a next step to fully understand these effects in the translational context of a contraceptive, given that women taking an EE-DRSP combination are typically ovary-intact.

The purpose of the current study was to determine the genetic and environmental contributions to the development of prosocial behavior in children using a population of 356 twins at 8 years of age. The study also aimed to examine whether qualities of parenting (specifically authoritarian and authoritative parenting styles) were phenotypic predictors of prosocial behavior. Both parent-reports and objective ratings of global prosocial behavior were used. Results supported prosocial behavior as a genetically-influenced trait with heritability estimates of 44% and 68% for parent reported and observed prosocial behavior, respectively. Data also suggested prosocial behavior as an environmentally-influenced trait. As hypothesized, authoritative parenting was moderately correlated with parent-reported prosocial behavior and authoritarian parenting was found to be low-to-moderately negatively correlated with parent-reported prosocial behavior. Multi-variable regressions demonstrated that authoritative parenting was significantly predictive of increased parent-reported prosocial behavior but authoritarian parenting was not predictive of decreased parent reported prosocial behavior. However, observed prosocial behaviors were largely independent of both authoritative and authoritarian styles of parenting.

Time spent alone is a topic that has been studied in great detail, particularly the manner in which it is spent and the effect it has during the adolescent stage of life. Similarly, stress levels in adolescents have always been a topic of interest because of the effects they could have on the individual later in adulthood. Oddly enough however, the two areas of study have never been looked at in relation to one another. This study will look at different types of alone time as possible stressors in a community sample (N=82) of adolescents transitioning to college. The data on time alone and stress levels was collected through diary reports over a period of 3 days. The analysis only yielded significant effects for females and only for specific categories. It was found that females experience the lowest amount of perceived stress when they are alone and want to be alone, they have more negative affect when their desired environment differs from their current situation, and more positive affect in both the alone incongruence and not alone congruence situations. These results indicate that only women experience stress and affect changes when they encounter different congruent and incongruent environments.

This study examined the cross-sectional and longitudinal associations among diurnal cortisol rhythms and sleeping patterns in adolescents. 79 participants completed the study over three days during the spring semester of their senior year in high school, and 76 of these subjects participated again over three days during the fall semester of their freshman year in college. They completed daily saliva samples and diary entries, while wearing an actigraph to obtain objective measurements of sleep duration and efficiency. Cross-sectionally, longer sleep duration was associated with a lower cortisol awakening response, a smaller area under the cortisol curve, and a steeper cortisol slope. Longitudinally, there was no significant relationship between sleep duration and these cortisol parameters. Moreover, sleep efficiency was not associated with cortisol parameters cross-sectionally nor longitudinally. Results suggest associations between concurrent sleep duration and cortisol patterns, and may have significant impact on understanding adolescents' physiological response to stress.

Childhood trauma has been linked to an increased risk of chronic pain in adulthood. One potential mechanism is via childhood trauma's impact on the hypothalamic-pituitary-adrenal axis (HPA) response to stress, reflected in changes in salivary cortisol levels (Nicolson et al., 2010). This study sought to determine the relations between childhood trauma, increases in cortisol levels following induced pain, and pain perceptions in adults with fibromyalgia, a chronic pain condition. It drew on data collected from participants enrolled in an investigation comparing the effectiveness of behavioral treatments for chronic pain. Before receiving treatment, participants attended a laboratory session during which they first rested, and then were exposed to heat stimuli to assess pain threshold and tolerance. Saliva samples were collected from each participant immediately following the rest, and twice during pain induction. Fibromyalgia participants with a history of childhood trauma were expected: 1) to report lower pain threshold and tolerance levels (i.e., have higher pain sensitivity), 2) to exhibit a higher resting cortisol level, and 3) to have greater increases in cortisol in response to acute pain induction than fibromyalgia participants without a history of childhood trauma. Findings showed that childhood trauma scores were: 1) related to lower pain tolerance (but not pain threshold), 2) unrelated to resting cortisol levels, and 3) unrelated to changes in cortisol in response to pain induction and pain tolerance, contrary to prediction. However, a subtype of childhood trauma, i.e., emotional maltreatment: 1) predicted lower pain tolerance, and 2) moderated the cortisol changes over time in response to pain induction during the laboratory session in the expected direction. That is, individuals who reported higher levels of childhood emotional maltreatment showed greater cortisol responses to the pain induction than individuals who reported lower levels of exposure to emotional maltreatment. Cortisol responses did not relate to pain perception. Thus, childhood emotional trauma predicted greater pain sensitivity and cortisol reactivity, but cortisol did not relate to pain perception. The findings suggest that early childhood trauma predicts cortisol reactivity and pain sensitivity, but that cortisol reactivity is not a mediator in the trauma-pain relation.

Alcohol use remains a large part of collegiate life and is a major public health concern. Alcohol use generally peaks during the early twenties and declines with age. These declines, referred to as "maturing out," are presumed to be the result of the acquisition of adult roles (e.g. marriage, parenthood, employment) incompatible with alcohol use. Recent empirical evidence suggests that variables other than role transitions (e.g. personality) during emerging adulthood may also be important in understanding this process. Conceptually, changes in identity that occur during emerging adulthood may also be linked to the process of maturing out of heavy drinking, though no studies have yet addressed this possibility. Utilizing data from a large sample of graduating college students during senior year and the two following years (N = 907), the current study examined relations between aspects of emerging adult identity development (identity exploration, instability, self-focus, feeling in-between, and experimentation/possibilities) and drinking outcomes (alcohol use and problems). Using multiple regression, changes in emerging adult identity development accounted for significant variability in alcohol use over and above relationship and employment status. Decreases in experimentation/possibilities significantly predicted decreases in alcohol use. Conversely, increases in feeling in-between significantly predicted decreases in alcohol use. The findings have important implications for both theories of "maturing out" and the development of prevention and early intervention efforts targeting alcohol abuse during this high-risk developmental period.

Full Disclosure, an honors thesis painting exhibition presented by Bachelor of Fine Arts candidate, Natalie Saez, strives to visually document the mental progression of people undergoing the transformative process of art therapy. Although often times a term that brings people on edge under certain circumstances, full disclosure brings to light information that otherwise would not have been expressed. In this same way, the process of art making - specifically referring to art therapy - presents a form of full disclosure. Varying stylistic approaches ranging from naturalistic to more abstracted portraits within the exhibition serve as a way to depict the uninhibited expression that results from the creative process.

The transition from high school to college is associated with considerable life strain for adolescents, including higher reported levels of daily stress and negative affect (NA), and alterations in stress physiology have been linked to poor health. The purpose of this thesis was to use an ecological momentary assessment design to study associations between momentary experiences of negative affect and cortisol levels in a sample of adolescents transitioning to college. I also examined the potential moderating effects of two potential vulnerability or protective factors, alone status and perceived social support from friends. Adolescents provided salivary samples and completed paper-and-pencil diary reports of socioemotional experiences and alone status five times per day for three consecutive weekdays, as well as completed self-report questionnaires on perceived social support from friends. Within-person increases in momentary negative affect were associated with momentary cortisol reactivity. Alone status significantly moderated this association such that the association between momentary negative affect and momentary cortisol levels was only significant when individuals were with others and not when they were alone. Perceived social support from friends did not significantly moderate the within-person associations between negative affect and momentary cortisol levels. The findings add to our understanding of physiological correlates of socioemotional experiences, as well as contexts in which these associations may be exaggerated or attenuated. The findings inform our understanding of potential pathways by which physiological reactivity to socioemotional experiences may affect the health of adolescents as well as how prevention efforts could reduce potential poor health outcomes associated with heightened stress reactivity.

This study examined whether social support available to parents moderated the heritability of parent-reported social approach at 12 months (N = 286 twin pairs, 52.00% female) and social competence at 30 months (N = 259 twin pairs, 53.30% female). Genetic and environmental covariance across age is also reported. Social support consistently moderated genetic influences on children’s social approach and competence, such that heritability was highest when parents reported low social support. Shared environment was not moderated by social support and explained continuity across age. Findings provide further evidence that genetic and environmental influences on development vary across context. When parents are supported, environmental influences on children’s social competence are larger, perhaps because support helps parents provide a broadly promotive environment.