A Recent Bottleneck of Y Chromosome Diversity Coincides With a Global Change in Culture
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50–100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192–307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47–52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.
- Author (aut): Karmin, Monika
- Author (aut): Saag, Lauri
- Author (aut): Vicente, Mario
- Author (aut): Wilson Sayres, Melissa
- Author (aut): Jarve, Mari
- Author (aut): Talas, Ulvi Gerst
- Author (aut): Rootsi, Siiri
- Author (aut): Ilumaee, Anne-Mai
- Author (aut): Maegi, Reedik
- Author (aut): Mitt, Mario
- Author (aut): Pagani, Luca
- Author (aut): Puurand, Tarmo
- Author (aut): Faltyskova, Zuzana
- Author (aut): Clemente, Florian
- Author (aut): Cardona, Alexia
- Author (aut): Metspalu, Ene
- Author (aut): Sahakyan, Hovhannes
- Author (aut): Yunusbayev, Bayazit
- Author (aut): Hudjashov, Georgi
- Author (aut): DeGiorgio, Michael
- Author (aut): Loogvaeli, Eva-Liis
- Author (aut): Eichstaedt, Christina
- Author (aut): Eelmets, Mikk
- Author (aut): Chaubey, Gyaneshwer
- Author (aut): Tambets, Kristiina
- Author (aut): Litvinov, Sergei
- Author (aut): Mormina, Maru
- Author (aut): Xue, Yali
- Author (aut): Ayub, Qasim
- Author (aut): Zoraqi, Grigor
- Author (aut): Korneliussen, Thorfinn Sand
- Author (aut): Akhatova, Farida
- Author (aut): Lachance, Joseph
- Author (aut): Tishkoff, Sarah
- Author (aut): Momynaliev, Kuvat
- Author (aut): Ricaut, Francois-Xavier
- Author (aut): Kusuma, Pradiptajati
- Author (aut): Razafindrazaka, Harilanto
- Author (aut): Pierron, Denis
- Author (aut): Cox, Murray P.
- Author (aut): Sultana, Gazi Nurun Nahar
- Author (aut): Willerslev, Rane
- Author (aut): Muller, Craig
- Author (aut): Westaway, Michael
- Author (aut): Lambert, David
- Author (aut): Skaro, Vedrana
- Author (aut): Kovacevic, Lejla
- Author (aut): Turdikulova, Shahlo
- Author (aut): Dalimova, Dilbar
- Author (aut): Khusainova, Rita
- Author (aut): Trofimova, Natalya
- Author (aut): Akhmetova, Vita
- Author (aut): Khidiyatova, Irina
- Author (aut): Lichman, Daria V.
- Author (aut): Isakova, Jainagul
- Author (aut): Pocheshkhova, Nymadawa
- Author (aut): Mihailov, Evelin
- Author (aut): Seng, Joseph Wee Tien
- Author (aut): Evseeva, Irina
- Author (aut): Migliano, Andrea Bamberg
- Author (aut): Abdullah, Syafiq
- Author (aut): Andriadze, George
- Author (aut): Primorac, Dragan
- Author (aut): Atramentova, Lubov
- Author (aut): Utevska, Olga
- Author (aut): Yepiskoposyan, Levon
- Author (aut): Marjanovic, Damir
- Author (aut): Kushniarevich, Alena
- Author (aut): Behar, Doron M.
- Author (aut): Gilissen, Christian
- Author (aut): Vissers, Lisenka
- Author (aut): Veltman, Joris
- Author (aut): Balanovska, Elena
- Author (aut): Derenko, Miroslava
- Author (aut): Malyarchuk, Boris
- Author (aut): Metspalu, Andres
- Author of afterword, colophon, etc. (aft): Federova, Sardana
- Author (aut): Eriksson, Anders
- Author (aut): Manica, Andrea
- Author (aut): Mendez, Fernando L.
- Author (aut): Karafet, Tatiana M.
- Author (aut): Veeramah, Krishna R.
- Author (aut): Bradman, Neil
- Author (aut): Hammer, Michael F.
- Author (aut): Osipova, Ludmila P.
- Author (aut): Balanovsky, Oleg
- Author (aut): Khusnutdinova, Elza K.
- Author (aut): Johnsen, Knut
- Author (aut): Remm, Maido
- Author (aut): Thomas, Mark G.
- Author (aut): Tyler-Smith, Chris
- Author (aut): Underhill, Peter A.
- Author (aut): Willerslev, Eske
- Author (aut): Nielsen, Rasmus
- Author (aut): Metspalu, Mait
- Author (aut): Villems, Richard
- Author (aut): Kivisild, Toomas
- Contributor (ctb): College of Liberal Arts and Sciences