This paper identified issues related to the production and use of knowledge in the conservation management of the Galapagos and provided frameworks for facilitating efficient engagement and actionable science to overcome knowledge gaps. The literature emphasizes the need for usable knowledge and knowledge exchange mechanisms to ensure that research findings are translated into practical solutions. The partnership between the Galapagos National Park and the Darwin Research Station has the potential to facilitate knowledge exchange through practices such as co production of knowledge, embedded researchers, or actionable science.