The present study examined associations between depressive symptoms among mothers, fathers,<br/>and adolescents and considered whether different associations emerged by parent and adolescent<br/>gender. In addition, the combination of maternal and paternal depressive symptoms was<br/>examined in relation to adolescents’ depressive symptoms. Participants were 246 families of<br/>Mexican-origin in two-parent households who resided in the Phoenix metropolitan area. Data<br/>were collected during home interviews at Time 1 and phone calls with adolescents at Time 2.<br/>Findings revealed concurrent bivariate associations between adolescents’ and mothers’ and<br/>fathers’ depressive symptoms. Further, mothers’ depressive symptoms predicted increases in<br/>adolescents’ symptoms two years later. However, there were no significant gender differences,<br/>and the combination of mothers’ and fathers’ depressive symptoms did not predict adolescents’<br/>depressive symptoms. These findings contribute to understanding the interrelations between<br/>Mexican-origin mothers’, fathers’, and adolescents’ depressive symptoms.