Jacques Loeb published The Mechanistic Conception of Life in 1912. Loeb's goal for the book was to further disseminate his explanations of organic processes, such as embryonic development and organisms orientations to their environments, which relied on physics and chemistry. Loeb also wanted to provide an alternative explanatory framework to vitalism and what he called romantic evolutionism, then both widespread. Loeb mined his work on tropisms and artificial parthenogenesis, both of which he considered central to biology, to show that physicochemical explanations accounted for some of the most perplexing organic phenomena. Thus, for those processes, anyone who appealed to vitalism or romantic evolutionism offered impotent explanations. The Mechanistic Conception of Life established Loeb's widespread reputation as a mechanist, both to the public and to generations of biologists.

Friedrich Tiedemann studied the anatomy of humans and animals in the nineteenth century in Germany. He published on zoological subjects, on the heart of fish, the anatomy of amphibians and echinoderms, and the lymphatic and respiratory system in birds. In addition to his zoological anatomy, Tiedemann, working with the chemist Leopold Gmelin, published about how the digestive system functioned. Towards the end of his career Tiedemann published a comparative anatomy of the brains of white Europeans, black Africans, and Orangutans, in which he argued that there were no appreciable differences between the structure of the brains of blacks, women, and white European men that would suggest they were intellectually different. Tiedemann also researched the embryonic development of the brain and circulatory systems of human fetuses.

Petr Kropotkin proposed the theory of Pleistocene ice age, alternative theories of evolution based on embryology, and he advocated anarchist and communist social doctrines in Europe during the nineteenth and twentieth centuries. He traveled in eastern Siberia and Manchuria from 1863 until 1867, and his subsequent publications about that area's geography became authoritative until the middle of the twentieth century. Kropotkin argued that his geographic and geologic observations in Asia, Finland, Sweden, and Canada, supported the theory of Pleistocene continental glaciation, often called the ice age. He was one of the first to study the ancient geography and climate of the Quaternary period, which spans from 2.5 million years ago until the present. Around the turn of the nineteenth century, Kropotkin offered what he said were complementary amendments to Charles Darwin's 1859 theory of evolution by natural selection. Kropotkin employed a variety of arguments from natural history, embryology, and geography to support his theory of mutual aid, which he argued was a positive mechanistic addition to the theory of evolution.

Victor Jollos studied fruit flies and microorganisms in Europe and the US, and he introduced the concept of Dauermodifikationen in the early 1900s. The concept of Dauermodifikationen refers to environmentally-induced traits that are heritable for only a limited number of generations. Some scientists interpreted the results of Jollos's work on Paramecium and Drosophila as
evidence for cytoplasmic inheritance. Jollos was forced to emigrate from Germany to the United States due to anti-semitic government policies in the early 1930s. Nevertheless, his work on Dauermodifikationen remained central to theoretical discourse among German zoologists concerning heredity, development, and evolution.

Julius von Sachs helped establish plant physiology through his experiments in latter nineteenth-century Germany. Sachs infused the inchoate discipline of plant physiology with experimental techniques and a mechanistic stance, both of which cemented his place as one of the discipline s founders. Sachs trained a generation of plant physiologists, and his stress on experimentation and mechanism influenced biologists in other disciplines, especially embryologist Jacques Loeb.

Vertebral osteology varies greatly among snake species. This variation may be related to specialization in microhabitat and prey-capture. Radiographs of eight preserved male specimens were taken in order to analyze the vertebral length and morphology of snakes which exhibit extreme characteristics in microhabitat utilization and prey-capture methods (highly arboreal, effective constrictor). This group includes two representatives each from four major families within Serpentes: Boidae, Pythonidae, Viperidae, and Colubridae. The four boids and pythons are effective constrictors, while the four vipers and colubrids are non-constricting. One specimen of each pair is highly arboreal, while the other is terrestrial. Findings support previous research in that constrictors had larger total numbers of vertebrae than non-constrictors. When average maximum adult length and morphology of axial musculature was taken into consideration, however, flexibility gained by vertebral number alone does not theoretically confer a mechanical advantage during constriction, at least among the specimens examined. All arboreal specimens had tails with a greater number of vertebrae than their con-familial terrestrial counterpart, implicating greater flexibility in the caudal region as an important characteristic for arboreality across taxa. Examination of segments of 10 vertebrae revealed that the greatest vertebral elongation occurred at the midpoint of the thoracic region. Reduction in size and length of tail vertebrae appears to occur independently of thoracic vertebrae. Colubrids, specifically, demonstrated a unique caudal vertebral elongation pattern which could potentially be advantageous for quick locomotion. These results indicate that caudal morphology may be more important in behavioral specialization than previously thought.

In the 1950s-60s, the United States performed nuclear testing 60 miles north of Las Vegas. The prevailing winds carried radiation from those tests across the United States. It didn't take long for groups of people to begin developing cancer, possibly as a side effect of the testing. In 1990, Congress established a program to compensate downwind victims of the test site. But one portion of one county in Arizona was never compensated, despite the impact cancer had in the area. This documentary is their story. (Documentary and website accessible at downwinddocumentary.com)