On the Impacts of Societal Lead Exposure in Childhood on the Incidence and Development of Age-Related Neurological Disorders

Description
This project examines the relationship between population-level childhood lead exposure and the incidence of Alzheimer's later in life, and proposes the creation of a paired study using existing data sources that will mature within the next decade to determine individual-level relationships between childhood lead exposure and Alzheimer's incidence.
Date Created
2024-05
Agent

Effect of Thermoelectric Freeze Concentration on Cost and Sensitivity of Point of Care Diagnostics

Description

Point of Care diagnostics are low-cost methods to diagnose these illnesses, but they are generally only effective when the infection has begun to cause symptoms. Concentrating biological samples has been proven to increase the sensitivity of POC tests and could

Point of Care diagnostics are low-cost methods to diagnose these illnesses, but they are generally only effective when the infection has begun to cause symptoms. Concentrating biological samples has been proven to increase the sensitivity of POC tests and could allow for earlier diagnosis to help monitor the spread of disease. This study reviewed the benefits of freeze concentration over other techniques to process samples in rural areas with limited infrastructure. Additionally, it analyzed the efficiency of thermoelectric devices as the cooling source for freezing. This analysis was conducted reviewing literature on the benefits of concentrating biological samples, software modeling the thermodynamics of a freeze concentrated system, and evaluating a physical model of this process. The software model established trends in altering L/D ratios of sample tubes and thermoelectric temperature. The physical model was successful in increasing the concentration of a red food dye solution through freezing with a thermoelectric device, showing this technique could be beneficial for minimal and efficient concentration devices.

Date Created
2023-05
Agent

Predicting Patient No-Shows With the Added Factor of Telemedicine

Description

In the following paper, I aim to form relationships between different patient factors and no-show rates. The culmination of these relationships will then be used in a logistic regression model. Data collected from a survey at 26 HonorHealth clinics were

In the following paper, I aim to form relationships between different patient factors and no-show rates. The culmination of these relationships will then be used in a logistic regression model. Data collected from a survey at 26 HonorHealth clinics were analyzed using odds ratios and relative risk methods. Of 310,307 visits collected, 22,280 of them were no shows (7.2%), an 11% decrease from national averages (18.8%). This fueled the study, along with a grant filed by HonorHealth looking at the impact of telehealth on the working poor. A binary logistic regression method was run over the data, and less than 1% of patients' no-shows were predicted correctly. By adding factors, and improving the diversity in the data collected, model accuracy can be improved.

Date Created
2022-05
Agent