Gangs present a wide array of consequences, both for society as a whole and for gang members themselves. Addressing factors that influence gang membership is of critical importance; however, very little research to date has sought to understand the relationship between spirituality, religion, and gang membership, instead focusing on general deviance. The goal of the present study is to bridge this gap by addressing two research questions: 1. what is the relationship between spirituality and gang membership? And 2. what is the relationship between formal religious participation and gang membership? In order to answer these questions, the current study utilizes Pathways to Desistance, a longitudinal study of adjudicated youth and young adults in Philadelphia, Pennsylvania and Phoenix, Arizona. Logistic regression indicates that spirituality, not formal religious participation, is associated with decreased odds of gang membership in the first two years following adjudication. In addition, increased levels of antisocial peer deviance are significantly associated with increased odds of gang membership. Together, these results indicate that reorienting gang members away from their deviant peers, fostering new, prosocial connections, and encouraging spiritual ideas such as personal closeness to a higher power and feelings of spiritual support may help decrease their odds of continuing participation in gang life. These findings support the continuation of faith-based gang treatments, but do not support formal religious practices (such as church services) as a focus of these treatments. Future research should collect original data, including qualitative interviews about gang members’ perceptions of and relationship with religion and spirituality, as well as utilize Pathways to Desistance in its full seven-year capacity in order to further understand the nuances of this relationship.