The central focus of this dissertation was to build on prior research that has underscored the significance of investigating culturally informed values and beliefs to promote racial-ethnic minority youths’ adjustment. In particular, Study 1 examined how Mexican-origin adolescents’ endorsements of familism values contributed to and moderated established theoretical associations within the achievement motivation process (i.e., contextual environment/individual factors, motivational beliefs, achievement-related strategies) and ultimately informed educational adjustment over time, or 5 years postpartum. Findings from Study 1 supported hypotheses regarding the dual role of familism values as both a promotive and protective factor throughout the achievement motivation process. Importantly findings highlight familism as an important cultural asset to consider as a potential facilitator of Mexican-origin adolescent mothers’ postpartum educational attainment. In addition to examining the promotive and protective function of familism, Study 2 explored how constellations of culturally informed promotive and protective factors, based on familism values, familial ethnic socialization, mothers’ and adolescents’ education aspirations, and social support (from family, peers, and dating partners), directly informed Mexican-origin adolescent mothers’ educational adjustment postpartum. Three distinct profiles emerged across social, aspirational, and familial domains, when adolescents were in their third trimester of pregnancy. Profiles were distinguished by unique patterns among study variables as a function of different levels of assets and resources. Furthermore, coresidency and economic hardship emerged as significant predictors of membership into latent profiles; and membership in specific profile groups significantly predicted educational attainment five years postpartum. Patterns of promotive/protective factors identified in the current study illustrate the importance of considering how the combination of multiple factors, across culturally salient domains, work in tandem to inform Mexican-origin adolescent mothers’ long-term educational attainment. Overall study findings offer a comprehensive insight into how familism values and other culturally informed factors contribute to the achievement motivation process and educational adjustment of pregnant and parenting Mexican-origin adolescent.