The Relation of Schizotypy and Aberrant Salience to Social Cognition as Assessed Through Responses to Video-Taped Interpersonal Interactions: A Cross-Sectional Study

Although social cognitive deficits are considered a hallmark trait of schizophrenia, research on schizotypy and social cognition is inconsistent. The present study examines the associations among schizotypy, aberrant salience, and social cognition. Schizotypy and aberrant salience were assessed continuously using the Schizotypal Personality Questionnaire Brief Revised (SPQ-BR) and the Aberrant Salience Inventory (ASI). Social cognition was examined using The Awareness of Social Inference Test (TASIT), an audio-visual paradigm that taps into multiple domains of social cognition. Data from 849 undergraduate students was analyzed. Results indicated that schizotypy overall was not associated with social cognitive deficits. However, when schizotypy was analyzed dimensionally, positive schizotypy was associated with social cognitive impairments. Further, aberrant salience was revealed to be consistently associated with social cognitive impairments, except when positive schizotypy was included in the model. This suggests the possibility that positive schizotypy could mediate the association between aberrant salience and social cognition. Overall, this study highlights the importance of focusing on positive schizotypy and aberrant salience in future investigations of social cognitive difficulties in psychosis.