Investigating the Role Of VEGF in Preeclampsia

Preeclampsia is a condition which arises during pregnancy and can lead to serious, even fatal, complications for the mother and baby. Annually, preeclampsia is responsible for about 50,000 total deaths worldwide, and countless other complications for both the mother and fetus. While high blood pressure and protein in the urine are key features, symptoms vary widely, and thus understanding, diagnosing, and treating the condition is of paramount importance. Due to the correlation between preeclampsia and high blood pressure, multiple groups have studied the role of angiogenic growth factors and preeclampsia. We performed an advanced PubMed search to select studies with both preeclampsia and VEGF, a key growth factor for angiogenesis, in the title. The results of examining a total of 65 articles led to the formation of this review article to articulate the studies as a whole and state of the research on VEGF and preeclampsia to date.