Exosomes are nanoscale extracellular vesicles that are shed from different cells in the body. Exosomes encapsulate several biomolecules including lipids, proteins, and nucleic acids, and can therefore play a key role in cellular communication. These vesicles can be isolated from different body fluids and their small sizes make them attractive in various biomedical applications. Here, we review state-of-the art approaches in exosome isolation and purification, and describe their potential use in cancer vaccines, drug delivery, and diagnostics.
Details
- Emerging Applications of Exosomes in Cancer Therapeutics and Diagnostics
- Inamdar, Sahil (Author)
- Nitiyanandan, Rajeshwar (Author)
- Rege, Kaushal (Author)
- Ira A. Fulton Schools of Engineering (Contributor)
- Digital object identifier: 10.1002/btm2.10059
- Identifier TypeInternational standard serial numberIdentifier Value2380-6761
- The final version of this article, as published in Bioengineering & Translational Medicine, can be viewed online at: http://onlinelibrary.wiley.com/doi/10.1002/btm2.10059/abstract?
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Inamdar, S., Nitiyanandan, R., & Rege, K. (2017). Emerging applications of exosomes in cancer therapeutics and diagnostics. Bioengineering & Translational Medicine, 2(1), 70-80. doi:10.1002/btm2.10059