Tyrosine Metabolism by the Human Microbiome
Description
Not only is Tyrosine one of the 20 amino acids that make proteins, but its catabolism also has many branches including a pathway that can be found in humans. Any mutations in the enzymes of this pathway can cause many disorders in humans including hereditary tyrosinemia type I. For this reason, understanding how tyrosine gets degraded in humans can help in developing therapies against disorders of the human tyrosine catabolism pathway. In this work, we explored what type of enzymes do microbes that reside within humans (the human microbiome) have to degrade tyrosine and how we can take advantage of the enzymes of the human microbiome for the betterment of human health and physiology.
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2021-12
Agent
- Author (aut): Toy, Amber
- Thesis director: Shah, Dhara
- Committee member: Shrivastava, Abhishek
- Committee member: Krajmalnik-Brown, Rosa
- Contributor (ctb): Barrett, The Honors College
- Contributor (ctb): School of Mathematical and Natural Sciences