Matching Items (43,913)
Description
This dissertation presents three essays in economics. Firstly, I study the problem of allocating an indivisible good between two agents under incomplete information. I provide a characterization of mechanisms that maximize the sum of the expected utilities of the agents among all feasible strategy-proof mechanisms: Any optimal mechanism must be a convex combination of two fixed price mechanisms and two option mechanisms. Secondly, I study the problem of allocating a non-excludable public good between two agents under incomplete information. An equal-cost sharing mechanism which maximizes the sum of the expected utilities of the agents among all feasible strategy-proof mechanisms is proved to be optimal. Under the equal-cost sharing mechanism, when the built cost is low, the public good is provided whenever one of the agents is willing to fund it at half cost; when the cost is high, the public good is provided only if both agents are willing to fund it. Thirdly, I analyze the problem of matching two heterogeneous populations. If the payoff from a match exhibits complementarities, it is well known that absent any friction positive assortative matching is optimal. Coarse matching refers to a situation in which the populations into a finite number of classes, then randomly matched within these classes. The focus of this essay is the performance of coarse matching schemes with a finite number of classes. The main results of this essay are the following ones. First, assuming a multiplicative match payoff function, I derive a lower bound on the performance of n-class coarse matching under mild conditions on the distributions of agents' characteristics. Second, I prove that this result generalizes to a large class of match payoff functions. Third, I show that these results are applicable to a broad class of applications, including a monopoly pricing problem with incomplete information, as well as to a cost-sharing problem with incomplete information. In these problems, standard models predict that optimal contracts sort types completely. The third result implies that a monopolist can capture a large fraction of the second-best profits by offering pooling contracts with a small number of qualities.
ContributorsShao, Ran (Author) / Manelli, Alejandro (Thesis advisor) / Chade, Hector (Thesis advisor) / Schlee, Edward (Committee member) / Kovrijnykh, Natalia (Committee member) / Arizona State University (Publisher)
Created2011
Description
Alzheimer's Disease (AD) is a debilitating neurodegenerative disease. The disease leads to dementia and loss of cognitive functions and affects about 4.5 million people in the United States. It is the 7th leading cause of death and is a huge financial burden on the healthcare industry. There are no means of diagnosing the disease before neurodegeneration is significant and sadly there is no cure that controls its progression. The protein beta-amyloid or Aâ plays an important role in the progression of the disease. It is formed from the cleavage of the Amyloid Precursor Protein by two enzymes - â and ã-secretases and is found in the plaques that are deposits found in Alzheimer brains. This work describes the generation of therapeutics based on inhibition of the cleavage by â-secretase. Using in-vitro recombinant antibody display libraries to screen for single chain variable fragment (scFv) antibodies; this work describes the isolation and characterization of scFv that target the â-secretase cleavage site on APP. This approach is especially relevant since non-specific inhibition of the enzyme may have undesirable effects since the enzyme has been shown to have other important substrates. The scFv iBSEC1 successfully recognized APP, reduced â-secretase cleavage of APP and reduced Aâ levels in a cell model of Alzheimer's Disease. This work then describes the first application of bispecific antibody therapeutics to Alzheimer's Disease. iBSEC1 scFv was combined with a proteolytic scFv that enhances the "good" pathway (á-secretase cleavage) that results in alternative cleavage of APP to generate the bispecific tandem scFv - DIA10D. DIA10D reduced APP cleavage by â-secretase and steered it towards the "good" pathway thus increasing the generation of the fragment sAPPá which is neuroprotective. Finally, treatment with iBSEC1 is evaluated for reduced oxidative stress, which is observed in cells over expressing APP when they are exposed to stress. Recombinant antibody based therapeutics like scFv have several advantages since they retain the high specificity of the antibodies but are safer since they lack the constant region and are smaller, potentially facilitating easier delivery to the brain
ContributorsBoddapati, Shanta (Author) / Sierks, Michael (Thesis advisor) / Arizona State University (Publisher)
Created2011
Description
This dissertation examines the performance of various federal departments on the success of their integration of personnel based on race and gender. It determines if there are variations in the success rate and explores the reasons for the variations based on the literature review and data analysis. The data used are federal employee data compiled by the U.S. Office of Personnel Management, Merit System Protection Board, and the Equal Employment Opportunity Commission through use of personnel surveys from 1979 through 2002 and annual reports. The study uses a cross-sectional model to test whether women and minorities in General Schedule grades 13 -15 have benefited from the implementation of Affirmative Action policy in their prospective agency over time. The effect of department size and affirmative action on the success rate of women and minorities was observed. The data shows that women at the GS 13 -15 grades have made significant gains in their participation rates at all of the departments within the study from 1979 - 2002. The gains made by minorities at the GS 13 -15 grades were not at the same rate as women. In several departments, the participation rates were either flat or decreased. The regression model showed that there is a linear relationship between the success of women and the success of minorities at the GS 13 -15 grade levels within federal departments.
ContributorsSaunders, Romona (Author) / Cayer, Joseph (Thesis advisor) / Alozie, Nicholas (Thesis advisor) / Lan, Gerald Z (Committee member) / Arizona State University (Publisher)
Created2011
Description
The effects of a long-term combat deployment on a soldier's physical fitness are not well understood. In active duty soldiers, combat deployment reduced physical fitness compared to pre-deployment status, but no similar research has been performed on Army National Guard soldiers. This study is the first to identify physical fitness changes in Arizona National Guard (AZNG) soldiers following deployment to a combat zone and to assess the relationships between physical fitness and non-combat injuries and illness (NCII). Sixty soldiers from the Arizona National Guard (AZNG) completed a battery of physical fitness tests prior to deployment and within 1-7 days of returning from a 12-month deployment to Iraq. Pre and post-deployment measures assessed body composition (Bod Pod), muscular strength (1RM bench press, back-squat), muscular endurance (push-up, sit-up), power (Wingate cycle test), cardiorespiratory fitness (treadmill run to VO2 peak), and flexibility (sit-and-reach, trunk extension, shoulder elevation). Post deployment, medical records were reviewed by a blinded researcher and inventoried for NCII that occurred during deployment. Data were analyzed for changes between pre and post-deployment physical fitness. Relationships between fitness and utilization of medical resources for NCII were then determined. Significant declines were noted in mean cardiorespiratory fitness (-10.8%) and trunk flexibility (-6.7%). Significant improvements were seen in mean level of fat mass (-11.1%), relative strength (bench press, 10.2%, back-squat 14.2%) and muscular endurance (push-up 16.4%, sit-up 11.0%). Significant (p < 0.05) negative correlations were detected between percentage change in fat mass and gastrointestinal visits (r = -0.37); sit-and-reach and lower extremity visits (r= -0.33); shoulder elevation and upper extremity visits (r= -0.36); and cardiorespiratory fitness and back visits (r= -0.31); as well as behavioral health visits (r= -0.28). Cardiorespiratory fitness changes were grouped into tertiles. Those who lost the greatest fitness had significantly greater number of NCII visits (8.0 v 3.1 v 2.6, p = .03). These data indicate a relationship between the decline in cardiorespiratory fitness and an overall increase in utilization of medical resources. The results may provide incentive to military leaders to ensure that soldiers maintain their cardiorespiratory fitness throughout the extent of their deployment.
ContributorsWarr, Bradley (Author) / Swan, Pamela (Thesis advisor) / Lee, Chong (Committee member) / Campbell, Kathryn (Committee member) / Erickson, Steven (Committee member) / Alvar, Brent (Committee member) / Arizona State University (Publisher)
Created2011
Description
With the introduction of compressed sensing and sparse representation,many image processing and computer vision problems have been looked at in a new way. Recent trends indicate that many challenging computer vision and image processing problems are being solved using compressive sensing and sparse representation algorithms. This thesis assays some applications of compressive sensing and sparse representation with regards to image enhancement, restoration and classication. The first application deals with image Super-Resolution through compressive sensing based sparse representation. A novel framework is developed for understanding and analyzing some of the implications of compressive sensing in reconstruction and recovery of an image through raw-sampled and trained dictionaries. Properties of the projection operator and the dictionary are examined and the corresponding results presented. In the second application a novel technique for representing image classes uniquely in a high-dimensional space for image classification is presented. In this method, design and implementation strategy of the image classification system through unique affine sparse codes is presented, which leads to state of the art results. This further leads to analysis of some of the properties attributed to these unique sparse codes. In addition to obtaining these codes, a strong classier is designed and implemented to boost the results obtained. Evaluation with publicly available datasets shows that the proposed method outperforms other state of the art results in image classication. The final part of the thesis deals with image denoising with a novel approach towards obtaining high quality denoised image patches using only a single image. A new technique is proposed to obtain highly correlated image patches through sparse representation, which are then subjected to matrix completion to obtain high quality image patches. Experiments suggest that there may exist a structure within a noisy image which can be exploited for denoising through a low-rank constraint.
ContributorsKulkarni, Naveen (Author) / Li, Baoxin (Thesis advisor) / Ye, Jieping (Committee member) / Sen, Arunabha (Committee member) / Arizona State University (Publisher)
Created2011
Description
Minimal information exists concerning dual language acquisition of three-year-old dual language learners (DLLs) during their first school experience and first systematic exposure to English. This study examined the Spanish and early English language development of young DLLs in the context of standardized measures and a story retell task. Participants included eight Spanish-English DLLs (7 females, 1 male, M age = 3 years, 8 months) attending Head Start, and their classroom teachers. Outcome measures for the children included composite and scaled scores on the Clinical Evaluation of Language Fundamentals Preschool-2 Spanish (CELF Preschool-2 Spanish; Wiig, Secord & Semel, 2009) and the parallel English measure (CELF Preschool-2; Wiig, Secord & Semel, 2005), and measures of lexical (NVT, NNVT, TNV, NW, NDW, TNW and TTR) and grammatical (MLUw) development. Proportion of classroom teachers' and paraprofessionals' Spanish, English and mixed language use was measured to contextualize the children's learning environment with regard to language exposure. Children's mean standardized Spanish scores at school entry were not significantly different from their mean scores in May; however, an increase in total number of verb types was observed. Children's English receptive, content, and structure mean standardized scores in May were significantly higher than their scores at school entry. Children were exposed to a high proportion of mixed language use and disproportionate amounts of English and Spanish exclusively. Children's performance was highly variable across measures and languages. The findings of the current study provide a reference point for future research regarding language development of three-year-old Spanish-English dual language learners.
ContributorsDubasik, Virginia L (Author) / Wilcox, M J (Thesis advisor) / Ingram, David (Committee member) / Lafferty, Addie (Committee member) / Macswan, Jeff (Committee member) / Arizona State University (Publisher)
Created2011
Description
ABSTRACT This study focuses on second language acquisition process amongst East Asian adult learners at an English and Culture Acquisition Program (ECAP) classroom. To understand their English learning experience, this study employs classroom observation, participant interview and document collection as research methods. The findings of this work suggest that ECAP does intend to help learners acquire English language proficiency in ways that were responsive to both the sociocultural backgrounds and individual needs of participants. ECAP also respects and promotes the learners' autonomy in the learning process. However, the program administrators and teachers still need to deepen their understanding of East Asian learners' sociocultural heritage and individual needs and improve facilitation accordingly.
ContributorsMi, Ximin (Author) / Danzig, Arnold (Thesis advisor) / Ovando, Carlos (Committee member) / Szecsy, Elsie (Committee member) / Arizona State University (Publisher)
Created2011
Description
United States and Mexico population statistics show clear evidence of return migration. This study uses qualitative data collected in a municipality in the State of Mexico during the summer of 2010 from families comprised of Mexican nationals and United States-born children post-relocation to Mexico. Using Portes and Zhou's theoretical framework on modes of incorporation, this study illustrates the government policy, societal reception and coethnic community challenges the first and second generation face in their cases of family return migration. This study finds that the municipal government is indifferent to foreign children and their incorporation in Mexico schools. Furthermore, extended family and community, may not always aid the household's adaptation to Mexico. Despite the lack of a coethnic community, parents eventually acclimate into manual and entrepreneurial positions in society and the children contend to find a place called home.
ContributorsMedina, Dulce (Author) / Menjivar, Cecilia (Thesis advisor) / Seline Szkupinski-Quiroga, Seline (Committee member) / Glick, Jennifer (Committee member) / Arizona State University (Publisher)
Created2011
Description
This dissertation examines associations between religious affiliation, religious community context and health of women and their children in Mozambique focusing on the following issues: (1) attending prenatal consultations and delivering children in a health facility; (2) women's symptoms of STDs; and (3) under-five mortality. Estimation of random intercept Poisson regression for the outcome about attending prenatal consultations demonstrated a favorable effect of affiliation to Catholic or Mainline Protestant and Apostolic religious groups. The concentration of Zionist churches in the community had a negative influence. Random intercept logistic regression was used to estimate the relationship between religion and institutional child delivery. Affiliation to Catholic or Mainline Protestant denominations as well as concentration of Catholic or Mainline Protestant churches in the community had some beneficial effect on giving birth in health clinics. The presence of Zionist churches in the community had some negative effect and that of other groups no significant influence. Random intercept logistic regression was also employed for investigating the influence of religion on women's symptoms of STDs. Belonging to the Catholic or Mainline Protestant church had some protective effect on reporting symptoms of STDs. There was no effect of religious context, except that the concentration of Other Pentecostal churches had a positive effect on reporting symptoms of SDTs. Event-history analysis was conducted for examining relationships between maternal religious affiliation with under-five mortality. Affiliation to Catholic or Mainline Protestant churches and to Apostolic denominations increased the odds of child survival, although, the influence of having a mother belonging to Catholic or Mainline Protestant churches lost statistical significance after accounting particularly for the average level of education in the community, for the period of 5 years preceding the survey date. Taken together, the results in this dissertation show some protective effect of religion that varies primarily by denominational group to which women are affiliated. They also indicate that religious community context may have some negative effect on health of women and children. The nature of the effect of religious community context varies with the type of outcome considered and the type of religious mixture in the community.
ContributorsCau, Boaventura Manuel (Author) / Agadjanian, Victor (Thesis advisor) / Hayford, Sarah (Committee member) / Yabiku, Scott (Committee member) / Arizona State University (Publisher)
Created2011
Description
Few measurement tools provide reliable, valid data on both children's emotional and behavioral engagement in school. The School Liking and Avoidance Questionnaire (SLAQ) is one such self-report measure developed to evaluate a child's degree of engagement in the school setting as it is manifest in a child's school liking and school avoidance. This study evaluated the SLAQ's dimensionality, reliability, and validity. Data were gathered on children from kindergarten through 6th grade (n=396). Participants reported on their school liking and avoidance in the spring of each school year. Scores consistently represented two distinct, yet related subscales (i.e., school liking and school avoidance) that were reliable and stable over time. Validation analyses provided some corroboration of the construct validity of the SLAQ subscales, but evidence of predictive validity was inconsistent with the hypothesized relations (i.e., early report of school liking and school avoidance did not predict later achievement outcomes). In sum, the findings from this study provide some support for the dimensionality, reliability, and validity of the SLAQ and suggest that it can be used for the assessment of young children's behavioral and emotional engagement in school.
ContributorsSmith, Jillian (Author) / Ladd, Gary W. (Thesis advisor) / Ladd, Becky (Committee member) / Thompson, Marilyn (Committee member) / Arizona State University (Publisher)
Created2011