This analysis explores what the time needed to harden, and time needed to degrade is of a PLGA bead, as well as whether the size of the needle injecting the bead and the addition of a drug (Vismodegib) may affect these variables. Polymer degradation and hardening are critical to understand for the polymer’s use in clinical settings, as these factors help determine the patients’ and healthcare providers’ use of the drug and estimated treatment time. Based on the literature, it is expected that the natural logarithmic polymer mass degradation forms a linear relationship to time. Polymer hardening was tested by taking video recordings of gelatin plates as they are injected with microneedles and performing RGB analysis on the polymer “beads” created. Our results for the polymer degradation experiments showed that the polymer hardened for all solutions and trials within approximately 1 minute, presenting a small amount of time in which the patient would have to remain motionless in the affected area. Both polymer bead size and drug concentration may have had a modest impact on the hardening time experiments, while bead size may affect the time required for the polymer to degrade. Based on the results, the polymer degradation is expected to last multiple weeks, which may allow for the polymer to be used as a long-term drug delivery system in treatment of basal cell carcinoma.
University Devils is a Founders Lab Thesis group looking to find a way for post-secondary institutions to increase the number of and diversity of incoming applications through the utilization of gaming and gaming approaches in the recruitment process while staying low-cost. This propelling question guided the group through their work. The team’s work primarily focused on recruitment efforts at Arizona State University, but the concept can be modified and applied at other post-secondary institutions. The initial research showed that Arizona State University’s recruitment focused on visiting the high schools of prospective students and providing campus tours to interested students. A proposed alternative solution to aid in recruitment efforts through the utilization of gaming was to create an online multiplayer game that prospective students could play from their own homes. The basic premise of the game is that one player is selected to be “the Professor” while the other players are part of “the Students.” To complete the game, the Students must complete a set of tasks while the Professor applies various obstacles to prevent the Students from winning. When a Student completes their objectives, they win and the game ends. The game was created using Unity. The group has completed a proof-of-concept of the proposed game and worked to advertise and market the game to students via social media. The team’s efforts have gained traction, and the group continues to work to gain traction and bring the idea to more prospective students.
We created a website with the intent to educate on the Valley Metro light rail. We showcased different aspects of the light rail and presented an argument as to why it should be utilized and expanded. We also created a social media account that highlights art pieces along the light rail.
Living a healthy and balanced life can be difficult for college students at Arizona State University due to the barrier of high cost of healthy food. To understand more about this problem we conducted research on the Tempe campus through surveys and virtual focus groups. We discovered that the cost of healthy food is one of the main barriers preventing students from eating healthy. We also learned that the students would be more willing to eat healthier if they could access healthy foods at a more reasonable price. Our solution to this problem was Eunoia, a service that allows students to receive discounts on healthy food and incentivize them to eat healthier in the future. Our company creates an innovative relationship between our customers, their private health insurance companies and local grocery stores throughout the Phoenix Metro area. Students at Arizona State University will be able to purchase healthy food items discounted by up to 30%. These discounts will be funded by their health insurance companies as well as the local grocery stores they purchase from. Our business model allows our customers to live healthier lives while also providing value to partnered health insurance companies and grocery stores. Once we established our business model, we spoke with students at Arizona State University and representatives from health insurance companies. Through these demographics, we received positive feedback and early traction with our idea. Our goal is to be able to implement our product in the Arizona State University community and then expand this product into a more general market to help all people live a pure and balanced life.
Student academic performance has far-reaching implications, such as lifetime earnings potential, that are beyond the immediate impact it may have on any individual student (Bureau of Labor Statistics [BLS], 2019). Colleges and universities also have a shared interest in the retention of their students as a poor reputation can depress enrollment and tarnish their brand. Public institutions have an especially large incentive for student success as many state and federal funding opportunities consider student retention and performance when allocating taxpayer dollars (Li, 2018). To assist in the mutual desire for students to succeed, the Calm Connection start-up venture formed with the goal of seamlessly integrating biofeedback therapy with a student’s unique education needs. Forming the foundation of the resulting Calm Connection app is software patented by NASA which allows for the collection and manipulation of biofeedback monitoring data on mobile devices with distinguishing features such as geolocation. For students, one of the largest barriers to effective learning is issues of focus and information retention, whether due to problems at home, conditions such as ADHD, or the high prevalence of test anxiety among students (Committee on Psychosocial Aspects of Child and Family Health et al., 2012). The repeated use of biofeedback therapy trains students to overcome these focus issues and works in conjunction with our app’s study aid and scheduling ability (Henriques et al., 2011). Among those surveyed and participants in follow-up focus groups, the Calm Connection app and its use of biofeedback monitoring has generated much interest and documented traction.
This paper explores the well-known Atkins Diet, as it also places a strong regulation on macromolecule consumption, specifically carbohydrates, in order to assist with the weight loss process. A review of available literature will be used to investigate: the history of the diet, necessity of macromolecule consumption, the impact this has on the individual biochemical pathways (glycolysis/gluconeogenesis) and the microbiome as a whole, as well as overall success rates and long-term health complications/benefits. Additionally personal statements from various individuals who have experience with the diet, myself included, will be incorporated into a holistic analysis of the effectiveness and longevity of the Atkins weight-loss strategy.
During the COVID-19 pandemic, increased burdens have been placed on the Arizona healthcare system, and its healthcare providers. Using a survey with a sample of N=308 prescribing providers and nurses in the Arizona healthcare system, the impact of COVID-19 on the wellbeing of healthcare providers was assessed. The survey used measures to evaluate for physical and emotional wellbeing, burnout, stressors associated with COVID-19, and work-life experiences, and found an overall negative impact on the wellbeing of healthcare workers during the COVID-19 pandemic with increased levels of reported stress and tiredness, concern for the health of family and loved ones, concern for the hardships of patients, lack of alignment between organizational priorities and personal values, and low levels of support and appreciation from socially and from leadership at work.
The 1980 Winter Olympic semi-final hockey game between the United States and Soviet Union changed the history of sporting events. The outcome took everyone by surprise, and it reinvigorated patriotism in the United States. It was and forever will be known as a miracle. The hockey game has only grown in popularity due to movies, books, and articles reminiscing on one of the greatest sports upsets in history. The United States-Russia rivalry has been a strong one since the very beginning of sports. The United States has always tried to keep up with the Russian talent, but in 1980 they took the Soviets by surprise, at height of the cold war. Not only were they rivals in sports, but enemies at a profound political level. Over the years, the tensions between the two countries have diminished, but recently they have increased again. Although these tensions continue to rise, these countries are able to battle for the top seed through sports. This has been shown throughout the years with one of the main competitions being the 1980 Winter Olympics semi-final hockey game.
Flora Vita is a digital platform that connects families to outdoor excursions, programmed activities and local events, encouraging the familial ecosystem to flourish within Arizona's vast environment. We curate unique opportunities that allow families to cultivate internal relationships with one another and form relationships with local like-minded families in pursuit of a healthy lifestyle.
COVID-19 has shocked the bedrock of society, impacting both human life and the economy. Accompanying this shock has been the psychological distress inflicted onto the general population as a result of the emotion strain stemming from isolation/quarantine policies, being sick with COVID-19, dealing with COVID-19 losses, and post-COVID syndrome and its effect on quality of life. The psychological distress has been experienced by the general population, but compared to middle age (30-50) and older adults (>50 years of age), it has been young adults (18-30 years old) who have been more psychologically affected (Glowacz & Schmits, 2020). Psychological distress, specifically anxiety and depression, has been exacerbated by feelings of uncertainty, fear of illness, losing loved ones, and fear of post-COVID syndrome. Post-COVID syndrome, as with other post-viral syndromes such as post viral SARS involve lingering symptoms such as myalgic encephalomyelitis or Chronic Fatigue Syndrome (CFS), and loss of motivation (Underhill, 2015). In addition to these symptoms, patients suffering from post-COVID syndrome have also presented brain inflammation and damaged brain blood vessels (Meinhardt et al., 2021), Endotheliitis (Varga et al., 2020), CV abnormalities and changes in glucose metabolism (Williams et al., 2020). CV abnormalities and changes in glucose metabolism are connected to chronic illnesses like diabetes and heart disease respectively. These chronic illnesses are then associated with higher risk for depression as a result of the stress induced by the symptoms and their impact on quality of life (NIMH, 2021). Further monitoring, and research will be important to gauge ultimate physiological and psychological impact of COVID-19.