Matching Items (43,913)
Description
Despite a wealth of academic literature critiquing current tensions within the Fair Trade (FT) movement, very little work has focused on examining the birth and evolution of the FT movement within the broader context of the international political economy (IPE), specifically in reference to the ideological and policy changes that ushered in an era of free trade and deregulated markets for both trade and finance. From such an optic, it is no longer enough to merely question the extent to which the market should be engaged. Rather, one must question whether the engagement of the market strips the movement of its power to affect long term development in local economies. Drawing upon the historical record, this thesis focuses attention on the complexity of the linkages that exist between political ideology, trade policy, and development. While Fair Trade is commonly understood to be a responsive effort to create more equitable trade relations with producers in the least developed countries, less emphasis is placed on understanding the state-centered political structures that contributed to a capitalist push-back and the implementation of today's liberalized trade policy, and yet to do so is absolutely critical if we are to gain a deeper understanding of the limits and constraints of Fair Trade. Full engagement with mainstream markets has led to robust growth in the FT market per annum, yet countries that are heavily engaged with the FT market show little evidence of development or poverty reduction at a macro-level. Thus, Fair Trade must define itself as more than principled opposition to labor exploitation if it is to present itself as a credible instrument of economic development.
ContributorsSugata, Michihiro (Author) / Simmons, William (Thesis advisor) / Stancliff, Michael (Committee member) / Haglund, LaDawn (Committee member) / Arizona State University (Publisher)
Created2011
Description
Treatment of cerebral aneurysms using non-invasive methods has existed for decades. Since the advent of modern endovascular techniques, advancements to embolic materials have largely focused on improving platinum coil technology. However, the recent development of Onyx®, a liquid-delivery precipitating polymer system, has opened the door for a new class of embolic materials--liquid-fill systems. These liquid-fill materials have the potential to provide better treatment outcomes than platinum coils. Initial clinical use of Onyx has proven promising, but not without substantial drawbacks, such as co-delivery of angiotoxic compounds and an extremely technical delivery procedure. This work focuses on formulation, characterization and testing of a novel liquid-to-solid gelling polymer system, based on poly(propylene glycol) diacrylate (PPODA) and pentaerythritol tetrakis(3-mercaptopropionate) (QT). The PPODA-QT system bypasses difficulties associated with Onyx embolization, yet still maintains non-invasive liquid delivery--exhibiting the properties of an ideal embolic material for cerebral aneurysm embolization. To allow for material visibility during clinical delivery, an embolic material must be radio-opaque. The PPODA-QT system was formulated with commercially available contrast agents and the gelling kinetics were studied, as a complete understanding of the gelling process is vital for clinical use. These PPODA-QT formulations underwent in vitro characterization of material properties including cytotoxicity, swelling, and degradation behaviors. Formulation and characterization tests led to an optimized PPODA-QT formulation that was used in subsequent in vivo testing. PPODA-QT formulated with the liquid contrast agent ConrayTM was used in the first in vivo studies. These studies employed a swine aneurysm model to assess initial biocompatibility and test different delivery strategies of PPODA-QT. Results showed good biocompatibility and a suitable delivery strategy, providing justification for further in vivo testing. PPODA-QT was then used in a small scale pilot study to gauge long-term effectiveness of the material in a clinically-relevant aneurysm model. Results from the pilot study showed that PPODA-QT has the capability to provide successful, long-term treatment of model aneurysms as well as facilitate aneurysm healing.
ContributorsRiley, Celeste (Author) / Vernon, Brent L (Thesis advisor) / Preul, Mark C (Committee member) / Frakes, David (Committee member) / Pauken, Christine (Committee member) / Massia, Stephen (Committee member) / Arizona State University (Publisher)
Created2011
Description
A fundamental motivation for this study was the underrepresentation of women in Science, Technology, Engineering and Mathematics careers. There is no doubt women and men can achieve at the same level in Mathematics, yet it is not clear why women are opting out. Adding race to the equation makes the underrepresentation more dramatic. Considering the important number of Latinos in the United States, especially in school age, it is relevant to find what reasons could be preventing them from participating in the careers mentioned. This study highlight the experiences young successful Latinas have in school Mathematics and how they shape their identities, to uncover potential conflicts that could later affect their participation in the field. In order to do so the author utilizes feminist approaches, Latino Critical Theory and Critical Race Theory to analyze the stories compiled. The participants were five successful Latinas in Mathematics, part of the honors track in a school in the Southwest of the United States. The theoretical lenses chosen allowed women of color to tell their story, highlighting the intersection of race, gender and socio-economical status as a factor shaping different schooling experiences. The author found that the participants distanced themselves from their home culture and from other girls at times to allow themselves to develop and maintain a successful identity as a Mathematics student. When talking about Latinos and their culture, the participants shared a view of themselves as proud Latinas who would prove others what Latinas can do. During other times while discussing the success of Latinos in Mathematics, they manifested Latinos were lazy and distance themselves from that stereotype. Similar examples about gender and Mathematics can be found in the study. The importance of the family as a motivator for their success was clear, despite the participants' concern that parents cannot offer certain types of help they feel they need. This was manifest in a tension regarding who owns the "right" Mathematics at home. Results showed that successful Latinas in the US may undergo a constant negotiation of conflicting discourses that force them to distance themselves from certain aspects of their culture, gender, and even their families, to maintain an identity of success in mathematics.
ContributorsGuerra Lombardi, Paula Patricia (Author) / Middleton, James (Thesis advisor) / Battey, Daniel (Committee member) / Koblitz, Ann (Committee member) / Flores, Alfinio (Committee member) / Arizona State University (Publisher)
Created2011
Description
This dissertation examines the use of color in lowrider car customizations. It studies the relationships among car owners, car painters, and car clubs in the process of selection, and manipulation of color. This research studies how color is constructed as an element for individual and community differentiation. Also included is the examination of the influence of car clubs in the design process, the understanding of color by car painters and car owners, and the cultural values associated with color in this community. This research argues that through the use, manipulation, and implementation of color as a visual/design element, lowriders challenge, transgress, and resist the preconceived notions of space, aesthetic hegemony, and social disparity they experience. In this case, color as a cultural expression, becomes a pivotal element to narrate and retell their stories of struggle and endurance, as well as to envision a different world. This research frames Chicana/o vernacular production, and color use as being central to the borderland experience of this community. Finally, this research follows the discourse of taste, as this concept has been used to create social categories of exotic otherness and the perpetuation of specific aesthetic epistemologies. In this context, it presents lowriders as expression of a Chicana/o network of vernacular border knowledge. This dissertation concludes by framing the Low n' Slow movement, in the context of healing and emancipating practices enacted by subjugated communities in order to survive, give sense to their reality, and to envision a more egalitarian world.
ContributorsCalvo, William (Author) / Giard, Jacques (Thesis advisor) / Boradkar, Prasad (Committee member) / Foster, David William (Committee member) / Arizona State University (Publisher)
Created2011
Description
A theme in the life experiences of ethnic minority adolescents is the perception of discrimination and its concomitant challenges. Although existing literature has examined the perception of discrimination in adolescents, little research has examined how the cultural and familial setting may heighten or alleviate the impact of perceived discrimination on psychological outcomes in Latino youth. The current study investigated how traditional cultural values and parent-adolescent relationships prospectively interact with perceptions of group based discrimination to influence Latino adolescent mental health, adjustment, and risky behaviors. Data used from the Parents and Youth Study included 194 Mexican American (MA) adolescents. Adolescents reported on their perceptions of group discrimination, endorsement of traditional Mexican cultural values, and parent-child relationships in the 7th grade (Time 1). The study also used indices of externalizing (mother report), internalizing, substance use and risky sexual behavior (adolescent report) in 10th grade (Time 2). The findings demonstrated that traditional Mexican cultural values, particularly familism, moderated the relationship between perceived group discrimination and adolescent sexual behavior. Additionally, a better overall relationship with mother and father buffered the detrimental effects of perceived group discrimination on risky sexual behavior. The current work discusses future directions of how the context of culture and family may shape an adolescent's response to perceived discrimination and the well-being of minorities.
ContributorsDiaz, Priscila (Author) / Saenz, Delia S. (Thesis advisor) / Kwan, Virginia S.Y. (Committee member) / Gonzales, Nancy (Committee member) / Geiser, Christian (Committee member) / Arizona State University (Publisher)
Created2011
Description
Cellular redox phenomena are essential for the life of organisms. Described here is a summary of the synthesis of a number of redox-cycling therapeutic agents. The work centers on the synthesis of antitumor antibiotic bleomycin congeners. In addition, the synthesis of pyridinol analogues of alpha-tocopherol is also described. The bleomycins (BLMs) are a group of glycopeptide antibiotics that have been used clinically to treat several types of cancers. The antitumor activity of BLM is thought to be related to its degradation of DNA, and possibly RNA. Previous studies have indicated that the methylvalerate subunit of bleomycin plays an important role in facilitating DNA cleavage by bleomycin and deglycobleomycin. A series of methylvalerate analogues have been synthesized and incorporated into deglycobleomycin congeners by the use of solid-phase synthesis. All of the deglycobleomycin analogues were found to effect the relaxation of plasmid DNA. Those analogues having aromatic C4-substituents exhibited cleavage efficiency comparable to that of deglycoBLM A5. Some, but not all, of the deglycoBLM analogues were also capable of mediating sequence-selective DNA cleavage. The second project focused on the synthesis of bicyclic pyridinol analogues of alpha-tocopherol. Bicyclic pyridinol antioxidants have recently been reported to suppress the autoxidation of methyl linoleate more effectively than alpha-tocopherol. However, the complexity of the synthetic routes has hampered their further development as therapeutic agents. Described herein is a concise synthesis of two bicyclic pridinol antioxidants and a facile approach to their derivatives with simple alkyl chains attached to the antioxidant core. These analogues were shown to retain biological activity and exhibit tocopherol-like behaviour.
ContributorsCai, Xiaoqing (Author) / Hecht, Sidney M. (Thesis advisor) / Gould, Ian R (Committee member) / Hartnett, Hilairy E (Committee member) / Arizona State University (Publisher)
Created2011
Description
In the late 1960s, Granger published a seminal study on causality in time series, using linear interdependencies and information transfer. Recent developments in the field of information theory have introduced new methods to investigate the transfer of information in dynamical systems. Using concepts from Chaos and Markov theory, much of these methods have evolved to capture non-linear relations and information flow between coupled dynamical systems with applications to fields like biomedical signal processing. This thesis deals with the application of information theory to non-linear multivariate time series and develops measures of information flow to identify significant drivers and response (driven) components in networks of coupled sub-systems with variable coupling in strength and direction (uni- or bi-directional) for each connection. Transfer Entropy (TE) is used to quantify pairwise directional information. Four TE-based measures of information flow are proposed, namely TE Outflow (TEO), TE Inflow (TEI), TE Net flow (TEN), and Average TE flow (ATE). First, the reliability of the information flow measures on models, with and without noise, is evaluated. The driver and response sub-systems in these models are identified. Second, these measures are applied to electroencephalographic (EEG) data from two patients with focal epilepsy. The analysis showed dominant directions of information flow between brain sites and identified the epileptogenic focus as the system component typically with the highest value for the proposed measures (for example, ATE). Statistical tests between pre-seizure (preictal) and post-seizure (postictal) information flow also showed a breakage of the driving of the brain by the focus after seizure onset. The above findings shed light on the function of the epileptogenic focus and understanding of ictogenesis. It is expected that they will contribute to the diagnosis of epilepsy, for example by accurate identification of the epileptogenic focus from interictal periods, as well as the development of better seizure detection, prediction and control methods, for example by isolating pathologic areas of excessive information flow through electrical stimulation.
ContributorsPrasanna, Shashank (Author) / Jassemidis, Leonidas (Thesis advisor) / Tsakalis, Konstantinos (Thesis advisor) / Tepedelenlioğlu, Cihan (Committee member) / Arizona State University (Publisher)
Created2011
Description
This work analyzed the role of interpersonal problems in interaction with ethnicity to predict psychotherapy outcome. A total of 262 individuals, who underwent psychotherapy at a counseling training facility, completed the Outcome Questionnaire-45 (OQ-45) and the reduced version of the Inventory of Interpersonal Problems (IIP-32). This study posited the following research question: Is the magnitude of the effect of ethnicity on treatment outcome conditional on certain IP dimensions (dominance or affiliation)? The purpose of this research was to determine whether or not ethnicity, represented by 3 ethnic groups (Whites, Hispanics, and Asians), was related to treatment outcome, and if this relationship was moderated by two interpersonal distress dimensions: dominance and affiliation. The results of the hierarchical regression analyses indicated that ethnicity did not predict post-treatment outcome gain, and neither affiliation nor dominance was a moderator of the relationship between outcome and ethnicity.
ContributorsJimenez Arista, Laura E (Thesis advisor) / Tracey, Terence (Committee member) / Kinnier, Richard (Committee member) / Claiborn, Charles (Committee member) / Arizona State University (Publisher)
Created2011
Description
This dissertation focuses on entrepreneurial and business performance indicators as determinants of Arizona charter schools' quality. The study utilizes a mixed-method inquiry with focus on qualitative research, exploration, and implementation studies. It draws data from surveys with charter operators performed by Education Team Partners (ETP). All survey results are drawn from the ETP database. The study reviews the genesis and evolution of charter schools. It reviews the social agreement within the context of public policy analysis, and the public-private partnership nature within the context of entrepreneurship and business management. It attempts to develop a research-based foundation for future action research to complement the newly introduced performance management plan (PMP) measurement and evaluation system in Arizona. The research includes four group indicators for measuring charter schools' business productivity and performance. They are studied in relation to three groups of indicators for measuring charter schools' quality. The case studies include two existing and two future charter schools. Study results indicate that all participating charter operators confirm the significance of the liquidity ratio in relation to any aspect of charter school quality covered in this study. The participants indicated a strong relationship between the capacities of their schools to utilize external resources and all indicators of charter school quality. This study draws two important conclusions. First, charter schools are business organizations, despite the fact that they receive public funds. Operationally, they differ substantially from district schools and government agencies and depend on market forces. Second, charter schools cannot survive inefficient management practices, as market forces tend to drive them out of business, regardless of academic success and student achievement levels. The intended implications from this study include: first, increased awareness about the importance of understanding business indicators in relation to charter school quality; second, the need for more research associated with the business and finance components of charter schools. As the body of collective knowledge about charter schools expands, the relationship between various business indicators to measures of quality should be routinely studied within larger populations, which may allow for an improved measurement system and applications of advanced statistical methods.
ContributorsHristov, Alexander (Author) / Cayer, N Joseph (Thesis advisor) / Thor, Eric (Committee member) / Edwards, Mark (Committee member) / Arizona State University (Publisher)
Created2011
Description
Finding the optimal solution to a problem with an enormous search space can be challenging. Unless a combinatorial construction technique is found that also guarantees the optimality of the resulting solution, this could be an infeasible task. If such a technique is unavailable, different heuristic methods are generally used to improve the upper bound on the size of the optimal solution. This dissertation presents an alternative method which can be used to improve a solution to a problem rather than construct a solution from scratch. Necessity analysis, which is the key to this approach, is the process of analyzing the necessity of each element in a solution. The post-optimization algorithm presented here utilizes the result of the necessity analysis to improve the quality of the solution by eliminating unnecessary objects from the solution. While this technique could potentially be applied to different domains, this dissertation focuses on k-restriction problems, where a solution to the problem can be presented as an array. A scalable post-optimization algorithm for covering arrays is described, which starts from a valid solution and performs necessity analysis to iteratively improve the quality of the solution. It is shown that not only can this technique improve upon the previously best known results, it can also be added as a refinement step to any construction technique and in most cases further improvements are expected. The post-optimization algorithm is then modified to accommodate every k-restriction problem; and this generic algorithm can be used as a starting point to create a reasonable sized solution for any such problem. This generic algorithm is then further refined for hash family problems, by adding a conflict graph analysis to the necessity analysis phase. By recoloring the conflict graphs a new degree of flexibility is explored, which can further improve the quality of the solution.
ContributorsNayeri, Peyman (Author) / Colbourn, Charles (Thesis advisor) / Konjevod, Goran (Thesis advisor) / Sen, Arunabha (Committee member) / Stanzione Jr, Daniel (Committee member) / Arizona State University (Publisher)
Created2011