Full metadata
Title
Development of a Novel Smart Contrast Agent for Magnetic Resonance Imaging
Description
Smart contrast agents allow for noninvasive study of specific events or tissue conditions inside of a patient's body using Magnetic Resonance Imaging (MRI). This research aims to develop and characterize novel smart contrast agents for MRI that respond to temperature changes in tissue microenvironments. Transmission Electron Microscopy, Nuclear Magnetic Resonance, and cell culture growth assays were used to characterize the physical, magnetic, and cytotoxic properties of candidate nanoprobes. The nanoprobes displayed thermosensitve MR properties with decreasing relaxivity with temperature. Future work will be focused on generating and characterizing photo-active analogues of the nanoprobes that could be used for both treatment of tissues and assessment of therapy.
Date Created
2014-05
Contributors
- Hussain, Khateeb Hyder (Author)
- Kodibagkar, Vikram (Thesis director)
- Stabenfeldt, Sarah (Committee member)
- Barrett, The Honors College (Contributor)
- Harrington Bioengineering Program (Contributor)
- School of Mathematical and Statistical Sciences (Contributor)
Topical Subject
Resource Type
Extent
35 pages
Language
Copyright Statement
In Copyright
Primary Member of
Series
Academic Year 2013-2014
Handle
https://hdl.handle.net/2286/R.I.22781
Level of coding
minimal
Cataloging Standards
System Created
- 2017-10-30 02:50:57
System Modified
- 2021-08-11 04:09:57
- 3 years 1 month ago
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